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5-Amino-1MQ has been associated with beneficial metabolic changes, including improved insulin sensitivity and altered lipid metabolism

Results Here, we describe how AtDUF569 bolsters plant responses to salt stress

This autophagic response reduces cell damage by activating the Keap1/Nrf2 antioxidant pathway, which is associated with Kelch-like ECH protein 1 and nuclear factor erythroid 2-related factor 2, thereby mitigating inflammation, endoplasmic reticulum stress, and apoptosis

These findings indicate that NDUFA1 plays a critical role in protecting against cisplatin-induced mitochondrial dysfunction and oxidative stress in tubular epithelial cell harboring the IDH1-R132H mutation