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Mutations and overexpression of the -syn gene induce conformational changes, transforming soluble monomers into insoluble toxic aggregates

The treatment with NP4 enhanced the level of pro-inflammatory M1 macrophages by 97% in comparison to the treatment with NP2

The elution gradient was a decreasing percentage of B from 80 to 4% during 17 min, holding at 5% of B for 3 min, and finally re-equilibrating the column at 80% of B for 4 min