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Description

NADP-dependent isocitrate dehydrogenase is inactivated by glutathionylation of a specific residue of cysteine by glutathione disulfide, which binds to a regulatory cysteine residue by trans-sulfuration

The balanced reaction rapidly shifts to the left side to lower the concentration of peroxyl radicals (LOO), and the autooxidation rate of -carotene get reduced (Iannone et al., 1998)