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Pain Med 2008

For most people, SQ shots are much less painful than IM shots because muscle tissue has a significantly higher density of nerve endings

The anti-arthritic effect of TQ (10 mg/kg in 0.1% DMSO) was observed in a rat model of arthritis with a marked reduction in the mRNA levels of toll-like receptor 2 (TLR2), TLR4, IL-1, NF-B, and TNF- [266]