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found that CAFs can secrete glycoprotein chitinase-3-like-1 (Chi3L1), which can enhance the recruitment of TAMs and induce their polarization towards the M2 type [42]

Inspect the intended injection site carefully before each injection, looking for small visible veins near the surfacechoosing a location slightly away from visible vasculature can reduce the chance of vessel puncture

Thus, we cannot rule out misclassification, mainly because we asked participants to indicate their average stool consistency during the last week of each study phase

This distinction is critical, especially in light of widespread fortification of foods with synthetic folic acid