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burgdorferi is truly an obligate extracellular pathogen, or if the spirochaete is capable of living, and possibly reproducing, inside the host cells, when the conditions outside the cells are not favourable (for instance due to presence of strong immunity or antibiotics)

plasma half-life is 2 minutes The principal routes of metabolism are methylation of the catechol and conjugation Drug Interactions: Do not add dobutamine to 5% Sodium Bicarbonate Injection or to any other strongly alkaline solution

Carrier-Mediated GSH Transport at the Blood-Brain Barrier and Molecular Characterisation of Novel Brain GSH Transporters Ram Kannan, Jian-R

Prolonged oxidative stress can lead to cellular damage, inflammation, and an increased risk of chronic diseases