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2023;13(11):e1446

With insurance but no savings card: Out-of-pocket costs often fall between $60 and $150 per month, depending on drug tier placement, deductibles, and coinsurance

The activities of DHAR and GR were also found to be increased under heat stress in temperature sensitive orchid Phalaenopsis (Ali et al., Similar to heat stress, low temperature stress also induces H 2 O 2 production in cells (Suzuki and Mittler, 2006) and is known to up-regulate transcripts, protein level and activities of different ROS-scavenging enzymes (Prasad et al., 1994

To functionally validate this theory, future research may integrate metabolomics with epigenetic editing tools, such as CRISPR-dCas9-TET1 [56, 70]