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doi:10.2337/dc12-2625 2

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Appetite Effects The question about appetite is interesting because the proposed mechanism could reasonably go either direction: Reduced lipogenesis and improved metabolic flexibility could produce secondary effects on appetite regulation NAD+ restoration has complex effects on hypothalamic appetite signaling Preclinical data do not consistently describe dramatic appetite changes In human use were it to become clinically available patient-reported appetite effects would be a relevant monitoring parameter, but the data do not currently support a strong a priori expectation

Its active functions are more varied, linked to the involvement of IgG in triggering various immune responses