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Consulting with a healthcare professional is essential to determine the most appropriate treatment strategy based on individual patient characteristics, medical history, and treatment goals

According to the National Institutes of Health, though most individuals do not need to make an extra effort to eat foods high in carnitine , some genetic or medical problems (such as angina or intermittent claudication) and certain drugs can prevent the body from producing enough of the nutrient, resulting in a shortage

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Although the study achieved an ORR of 18%, it was terminated early because of dose-dependent, on-target/off-tumor toxicity affecting skin, eyes, and ears, including one treatment-related death at the highest dose level, illustrating the narrow therapeutic window of differentiation antigens shared with normal melanocytes [187]