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The function of astrocytic dopamine receptors was long overlooked until we recently reported that activation of the astrocytic dopamine D2 receptor (DRD2) can suppress neuroinflammation in PD 23,24

Pyridoxal phosphate accepts amino groups from aspartate catalyzed by aspartate aminotransferase, and alanine catalyzed by alanine aminotransferase to form Schiffs base intermediates that are subsequently reduced to form pyridoxamine phosphate