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Ketorolac tromethamine injection is contraindicated for neuraxial (epidural or intrathecal) administration due to its alcohol content

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So it is restricted to a finite water volume within the body

1 Introduction Vitamin B12, or cobalamin, is a water-soluble vitamin, that plays an essential role in cellular metabolism, particularly in DNA synthesis, methylation processes, and mitochondrial functions ( Lactobacillus spp ) (Rucker et al., 2007)