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Regarding the composition of the peptide, the six N-terminal amino acids (KCRKEM) from TNFR1 were more positively charged, the six middle amino acids (FKQKLP) from IL-1R were more hydrophobic and positively charged, and the six C-terminal amino acids (YSTVYF) from the IL-6 receptor were neutral (Fig

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doi: 10.3389/fchem.2025.1536858 Received 29 November 2024 Accepted 27 January 2025 Published 19 March 2025 Volume 13 - 2025 Edited by Federica Aureli, National Institute of Health (ISS), Italy Reviewed by Eric Deconinck, Sciensano (Belgium), Belgium Maria Cristina Gaudiano, National Institute of Health (ISS), Italy Updates Copyright 2025 Blazewicz, Poplawska, Daniszewska, Piorunska and Karynski