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2003;37(4):281-4.[CrossRef] 52

PKM2 promotes cell survival and invasion under metabolic stress by enhancing warburg effect in pancreatic ductal adenocarcinoma

Think of it as a cellular security guard that identifies unstable molecules, known as free radicals, and neutralizes them before they can harm your DNA or cellular structures

An in vitro study revealed that AGEs binding to RAGE on macrophages and microglia promote oxidative stress by activating NF-KB, and MAPK, c-Jun N-terminal kinase (JNK), and p21RAS signaling pathways (197)