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Enhanced Muscle Growth and Repair Certain peptides, such as growth hormone-releasing peptides (GHRPs) and insulin-like growth factor 1 (IGF-1), can stimulate the production of growth hormone and promote muscle growth and repair

It has been studied for its potential role in nerve regeneration and brain recovery following injuries like traumatic brain injury (TBI) or stroke

Many involved combined treatments and lacked modern trial detail

IGF-1 treatment of Th17 cells decreases mitochondrial membrane potential and mROS production in an IGF-1R and IR dependent manner To determine if these IGF-1-mediated changes on Th17 cell mitochondrial membrane potential and mROS require signaling by IR, IGF-1R, or both, we differentiated Th17 cells in vitro from IGF-1R cKO mice or IR cKO mice, and littermate controls