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Data were visualized using MetaboAnalyst or ExpressAnalyst platforms ( Gene ontology (GO) terms were identified by GO Enrichment Analysis ( Quantitative reverse transcription-polymerase chain reaction Gradient PCR was used to optimize the annealing temperature of gene-specific primers, identified from the literature or designed with primerBLAST ( Supplementary Table 1 )

FONG'S LIVE SESSION

EVs derived from M2-polarized microglia have been shown to improve learning and memory in both 5FAD mice and an AD model induced by intracerebroventricular A142 injection, with efficacy demonstrated in the NORT, Morris water maze, Y-maze, and OFT [102-103]

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