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Hyperbaric Oxygen Therapy (HBOT) is a medical treatment where patients breathe pure oxygen in a high-pressure chamber

The phenols, bioactive compounds, enzymes, peptides, protein, and other derivatives of phytochemicals have potential against free radicals and viral agents (6, 11)

Overall, this work proposed a convenient, safe, and effective rectal drug delivery strategy, providing a new candidate for the prevention and treatment of radiation-induced proctitis, and also providing a reference for the design of multifunctional local delivery systems in radiation-associated tissue injury