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Internationally: NICE guidelines are often used as a reference point by healthcare professionals and policymakers in other countries

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Thus, the healing of the esophagocutaneous, gastrocutaneous, duodenocutaneous, colocutaneous, vesicovaginalis, and rectovaginalis fistulas, assessed grossly, biomechanically and microscopically means demonstration of the both external and internal fistulas healing and consequently, the realization of the simultaneous healing of different tissues

The study also opens the door for more future research about the administration routes of vitamin B12 and other vitamins