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External references for further reading: the FDA investigation into diet and canine heart disease and Tufts University veterinary nutrition research.

and 4) inhibits the pro-oxidant enzyme NADPH-oxidase that generates reactive oxygen species (ROS) ( To model inadequate zinc intake prevalent in human populations, both severe and marginal zinc deficient diets have been used in animal studies to examine various health outcomes, including the effects on DNA damage and integrity

Moreover, surgical treatment involves deep brain stimulation (DBS) and lesioning surgery, out of which the former could be effective for patients of PD in the advanced stage who no longer respond adequately to the medicines