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doi: 10.1016/j.clinre.2015.01.003

In wildtype mice, optogenetic inhibition of GABAergic interneurons in the medial prefrontal cortex (mPFC) leads to cognitive deficits ( +/ ) or absent (PV / ) expression exhibit the core ASD-like symptoms ( In addition, Reelin is an extracellular matrix glycoprotein closely related to neural development, which is involved in the regulation of neuronal migration, synaptic plasticity and neural network formation ( 3.2 The relationship between GABAergic signaling pathway abnormalities and ASD 3.2.1 The synthesis, release, transport, and metabolism of GABA The biosynthesis of GABA primarily relies on the decarboxylation of glutamate catalyzed by GAD

10.1021/jf200251k J

Richard Horowitz What they found in a study a few years ago, in these autopsy studies of Alzheimer's and Parkinson's, important also for Parkinson's, they found biofilms, amyloid and P tau in these autopsy studies of these patients