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It's important to note that significant hypoglycaemia is uncommon with these medications unless they are combined with insulin or sulfonylureas, or during prolonged fasting

Reducing other stressors in the household can significantly aid recovery

Notably, the lower weight loss (-13.7%) observed in REDEFINE 2 among individuals with T2D suggests that the magnitude of benefit achieved with combined GLP-1 and amylin receptor agonism may depend on the underlying metabolic status, highlighting the need for a more nuanced understanding of the mechanisms governing treatment response [13]