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The ligand in this case is chosen to have a sequence, structure, or restriction site that can be used to capture a protein that will interact specifically with this DNA segment [223,232]

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However, there is clear evidence of mammalian hypothalamic-pituitary axes disruption caused by MPs and their composite EDCs that alter hormonal balance through feedback mechanisms (126, 127) ( Table 7 )

Uzi D et al found that inhibition of CHOP, a key protein of ER stress, could protect liver from APAP hepatotoxicity 31