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Products marketed outside approved channels are not subject to the same quality and safety controls as approved medications, which increases variability and risk

Se is a component of about 25 enzymes including the GSH-Px family, thioredoxin reductases and selenoprotein P which provide antioxidant protection against ROS-driven cancer initiation and promotion, as well as some others (Zachara et al., 2006

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Using a 50% probability cutoff, the AHEAD Score achieved a specificity of 61.5% (107 out of 174 non-cases correctly identified) and a sensitivity of 63.3% (19 out of 30 cases correctly identified)