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Fc-containing fusion protein drugs predominantly target receptor-ligand interaction by acting as either antagonists to block receptor binding or agonists to directly stimulate receptor function, thereby reducing or increasing immune activity, respectively 11

Notably, a phase I clinical trial of the MCT1 inhibitor AZD3965 for advanced solid tumors (NCT01791595) has been completed, laying the groundwork for future clinical development

We'd also use it a lot in post-COVID, where you have an abnormal immune response or the immune system hasn't caught back up, and you can dial it up using Thymosin alpha-1 in a very safe way