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Subsequently, an in-depth investigation into the underlying mechanism of Crizotinib-induced hepatotoxicity was conducted through mRNA sequencing analysis

Sodium butyrate (NaB), an inhibitor of HDAC activity, is the most widely studied SCFA salt against DN (Gu et al., 2019)

The level of these metabolites in plasma, urine, and cerebrospinal fluid (CSF) is typically elevated with ALDH7A1 mutations ( dependent epilepsy. A similar situation is caused by MOCS2 mutations, which lead to molybdenum cofactor deficiency and sulphite accumulation