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Some previous studies supported our results

Masayuki Yamamotos lab identified halofuginone in a chemical library screen and demonstrated effective NRF2 suppression via suppression of prolyl-tRNA synthetase activity and amino acid starvation response [89]

10.1016/S0020-7292(01)00494-5 121 NikooS.EbtekarM.Jeddi-TehraniM.ShervinA.BozorgmehrM.KazemnejadS.et al (2012)

We have validated this approach in yeast ( Saccharomyces cerevisiae ), Staphylococcus aureus , Michigan Cancer Foundation-7 (MCF-7) and Madin-Darby canine kidney (MDCK) cells