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Description

Digitoxin was found to suppress HIF-1 in GBM stem cells with high specificity (160)

Thus, "isogenic transplantation" refers to the transfer of donor cells to a recipient who is genetically identical or sufficiently immunologically compatible with the donor to permit transplantation without undesirable adverse immunogenic reactions (e.g., to be detrimental to the interpretation of the immunological screening results described herein)