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In the same study, higher spermidine levels were associated with good water maze performances and decreased anxiety, whereas spermine had the opposite effect, suggesting differential roles for spermidine and spermine in behavioural outcome

Repeated measures one-way ANOVA and Tukeys honest significant difference tests were used to compare groups

4.0 mL + 0.2 mL NaOH, 2 mol/L): 0.050 Melting range: +189 to +200C Specific rotation: -16.5 to -21.4 Purity (enzymatically and iodometric): 98% Purity (iodometrically): 98% Loss on drying (+105C, 2 hours): 1% Glutathione, oxidized form (enzymatically): 1.5% Fe (bathophenanthroline): 5 ppm Heavy metals (as Pb, AAS): 5 ppm Methanol (GC): 50 ppm Aceton (GC): 50 ppm Ethanol (GC): 0.1% Stability: At +2 to +8C within specification range for 24 months

3.1 RONS 3.1.1 NMs Visualize RONS to Evaluate Macrophage Activity ROS are considered a series of chemically active substances generated from intracellular oxygen through electron transfer, primarily including hydrogen peroxide (H 2 O 2 ), hydroxyl radical (OH), hypochlorous acid (HOCl), and superoxide anion (O 2 ) [78]