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Brain Res 1034 : 1124 A pioneering paper reporting that TNF alpha potentiates glutamate neurotoxicity by blocking glutamate transporter activity

Additionally, remodeling of the ECM in TDLNs is also thought to occur as part of the pre-metastatic niche formation, but the mechanisms that underlie this process and their molecular players remain to be uncovered ( A single-cell analysis carried out in cells isolated from murine breast cancer models showed changes in immune modulation and metabolism in TDLNs (174)