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Mutations in the p53 gene occur in diverse human tumour types

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ATR ATR serine/threonine kinase: activates checkpoint signaling upon genotoxic stresses BEC bronchial epithelial cells Cardiolipin component of the inner mitochondrial membrane, part of complex IV, the cytochrome c oxidase in the OXPHOS process Carnitine essential cofactor that helps transport longchain fatty acids into the mitochondria so that they can be oxidized to produce energy in the form of ATP CD38 cyclic ADP ribose hydrolase, catalyzes the synthesis of ADP ribose (ADPR) and cyclic ADPribose (cADPR) from NAD+