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Inhibiting ferroptosis has been found to maintain MSC viability, enhance differentiation, and improve the efficacy of transplanted MSCs in various disease models (Liu J

In some embodiments, the carboxyl group of the C-terminus of the peptide is protected with a carboxyl protecting group and/or the Na-amino group of the peptide is protected with an amino protecting group

Mercury usually stays on the surface of sediments or soil and does not move through the soil to underground water

FERROPTOSIS-RELATED SIGNALING PATHWAYS IN CANCER DRUG RESISTANCE Oxidative damage-related signaling pathways Canonical GPX4-regulated signaling pathway GPX4, a key member of the glutathione peroxidase family, plays a critical role in the modulation of ferroptosis by converting lipid hydroperoxides into inert lipid alcohols, thus preventing their accumulation and protecting cellular membranes