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This is because benzyl alcohol loses its effectiveness as a preservative with repetitive use and exposure

Online communities promoting these compounds together lack medical or scientific oversight, and anecdotal reports should not be treated as evidence of safety or efficacy

L., & Dunn, M

Additionally, a randomized, double-blind, placebo-controlled trial in 2,588 healthy older adults with mild hyperhomocysteinemia found that daily supplementation with 500 g of vitamin B 12 and 400 g of folic acid for two years reduced blood homocysteine concentrations but had no benefit on depressive symptoms in those with or without depressive symptoms at baseline (110)