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The Role of Cancer Pre-Screening Scientific Rationale for Oncological Screening The proangiogenic properties of BPC-157 and TB-500 raise notable concerns regarding their use in individuals who may harbor subclinical or undiagnosed malignancies

Although dryness (sicca) of the eyes and mouth are the classically described features, dryness of other mucosal surfaces and systemic manifestations, including fatigue and arthralgia, are common ( Digestive involvement is frequent in pSS, including autoimmune disorders, such as chronic atrophic gastritis, esophageal motility dysfunction, lymphocytic colitis, primary biliary cholangitis and autoimmune hepatitis ( pSS-related atrophic gastritis and associated PA may require parenteral or sublingual vitamin B12 supplementation (2)

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Common clinic signs include: Chronic or recurring vomiting Diarrhea (often with mucus or blood) Weight loss Lethargy Poor coat quality Decreased appetite These symptoms often appear gradually and may come and go, making them easy to overlook at first