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Dysesthesia (Skin Sensitivity) A distinct side effect that has emerged primarily at higher doses of retatrutide is dysesthesia an altered, sometimes uncomfortable physical sensation on the skin, often described as mild tingling, burning, or hyper-sensitivity to touch

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The fact that cells might be able to synthesize NR from other NAD + -related molecules could also explain why NR can be found at micromolar concentrations in mammalian milk [40,105]