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[94] Pre-term infants are also at a higher risk of having various neurodevelopmental disorders such as cerebral palsy and autism, as well as psychiatric disorders related to attention, anxiety, and impaired social communication

Mechanistically, finasteride has been proven to be 5-R2 inhibitor by acting on alternative substrate for 5-R2 which is initially bound to highly stable complex of enzyme-bound NADP-dihydrofinasteride

But individual response varies based on baseline glutathione status, genetic polymorphisms in glutathione synthesis enzymes, and concurrent medications that affect redox balance

doi:10.1016/0014-4827(90)90108-m