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Extracellular vesicles (EVs) secreted by CHMP2A KO tumors were characterized by lower expression of MICA/B ligands [104]

Enzymes in the purine salvage pathway, such as adenine phosphoribosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT), are essential for Leishmania survival and have been explored as potential targets ( Leishmania has emerged as a promising target

The gut flora is considered to be a large secretory organ, which produces trimethylamine-N-oxide (TMAO), short-chain fatty acids and secondary bile acids by breaking down the ingested food