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[23] [24] The MHRA advises testing for B12 deficiency if symptoms or signs develop in patients taking metformin, and considering periodic monitoring in those at risk

10.1016/j.cmet.2016.09.013 92 MondalK.ChakrabortyP.KabirS

(5) As these agents become increasingly integrated into clinical practice, their effects on weight, metabolic regulation, and systemic inflammation carry important implications for orthopedic surgery