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Standard reconstitution for AOD-9604 AOD-9604 typically arrives as lyophilized (freeze-dried) powder in sealed vials, most commonly in 2mg or 5mg quantities

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The resulting capillary occlusion and ischemia further aggravate retinal damage while stimulating VEGF overexpression, which drives pathological neovascularization and increases the risk of vitreous hemorrhage and tractional retinal detachment in advanced DR (74)