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J Neuroimmune Pharmacol (2019) 14(1):13456

doi: 10.1038/s42003-020-01501-3 172 DeGolierKRDanisED'AntonioMCimonsJYarnellMKedlRMet al

Fragmentation reveals daughter ions representing partially coordinated fragments, confirming which atoms donate electrons to the copper center

In the classical pathway, the TNF receptor superfamily recruits RIPK1 through its death domain when caspase-8, the main executor of apoptosis, is inhibited genetically or pharmacologically