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The gap is in scale and independent replication

Gelt, Joe, Jim Henderson, Kenneth Seasholes, Barbara Tellman, and Gary Woodard

PM2.5, Fine Particulate Matter: A Novel Player in the Epithelial-Mesenchymal Transition

Indeed, treatment strategy using ACE2 analogs or vector containing ACE2 result in beneficial effects in diabetic nephropathy, hypertension, cardiac disease [37]