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Poster presented at AATS 102nd Annual Meeting, 2022

Dickey, S

As research on the role of astrocytes in neuronal energy metabolism continues to advance, several new trends are emerging in this field

In RPE of AMD patients, the expression of circSPECC1 is downregulated, and circSPECC1 insufficiency leads to oxidative stress-induced ferroptosis, depolarization, and irregular lipid metabolism via circSPECC1/miR-145-5p/CDKN1A axis, and then induces visual impairments and RPE anomalies and interrupts retinal homeostasis (Chen X