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During early development, flux through this cycle helps determine whether one-carbon units are used for (1) nucleotide synthesis ( supporting mitosis ), (2) formate production ( fueling methylation reactions ), or (3) glutathione regeneration ( buffering oxidative stress )

Speech therapy Many people with Parkinsons experience difficulties with speech, especially as the disease progresses

Methylation of the imidazole side chains of the alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity