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Despite its critical importance, magnesium deficiency is remarkably common, especially in individuals dealing with chronic physical stress, systemic inflammation, or gastrointestinal malabsorption

In epithelial cells, E-cadherin inhibits ferroptosis by mediating the interaction of intracellular NF2 (also called merlin) and Hippo signaling pathway while antagonizing the signal axis mediated by E-cadherin promotes ferroptosis through YAP [72]