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Lavelle and Sokol, 2020)

143 Unlike HIF1A, endothelial PAS domain protein 1 (EPAS1, also known as HIF2A) appears to promote ferroptosis in clear cell carcinoma cells through transcriptional upregulation of hypoxia-inducible lipid droplet-associated (HILPDA/HIG2), 144 a regulator of enriched lipids that contains polyunsaturated fatty acyl side chains

Antioxidants are nutrients that help to protect your body from the damage caused by free radicals - the toxic molecules that play a role in the development of diseases from cataracts to heart disease to arthritis

In the small intestine, VIC exists as ascorbate (predominant) and DHA, which is reduced to the ascorbate form in cells