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doi: 10.4049/jimmunol.0903586 252 NakayaMXiaoYZhouXChangJHChangMChengXet al

It is best known in metabolic and fat-cell research, and what sets it apart is that it can slip across cell membranes to reach its target inside the cell

Genetic mutations (e.g., SLC6A1 and SHANK3) have pleiotropic effects on the E/I balance, complicating target selection [112]

For example, researchers have complied genomics, metabolomics, proteomics, and microbiome analyses in a single framework to develop individualized dietary interventions for T2D ( FADS1 and FADS2 genes ( Major upstream causal factor is the genome, with metabolome, microbiome and other omics being mediators which are impacted by age, gender, demographic characteristics, and pharmacological intervention ( Integration of omics involves collection of data from various sources, i.e., biological structure (cell, organ, tissue), samples (urine, blood), conditions (time-points, experimental groups) etc