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Importantly, the researchers explored multiple possible explanations, including the idea that adipose tissue may sequester B12, meaning larger fat deposits could be trapping the vitamin away from the bloodstream and making measured levels appear lower

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However, evidence proved that orally administered L-carnitine was effective in alleviating fatigue syndrome induced by chronic metabolic disease and improving quality of life [25]

The data were further normalized to the median value of total lipid signals