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Patio P, et al

Challenges include an acidic microclimate inducing protein aggregation (neutralization with MgCO3), incomplete release of hydrophilics, and scale-up variability

doi:10.1016/j.apmr.2004.09.011 19

Kell DB & Pretorius E (2015) On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death