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Deficiency of MTH1 and/or OGG1 increases the accumulation of 8-oxoguanine in the brain of the App(NL-G-F/NL-G-F) knock-in mouse model of Alzheimers disease, accompanied by accelerated microgliosis and reduced anxiety-like behavior

Nrf1 and Nrf2 are members of the cap n collar-basic leucine zipper proteins (CNC-bZIP) that can trans -activate ARE (Kwong et al., 1999

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