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This intelligent hydrogel enables responsive release of H2O2 in the tumor microenvironment by specifically targeting the CD44 receptor on the surface of tumor cells

Consequently, there is a need for long-term studies with more substantial participant numbers to verify the sustained effectiveness of NADH and CoQ10 in treating ME/CFS [129]

In cancer cells, lactylation is commonly associated with the upregulation of gene expression to promote cancer progression, which is consistent with the phenotypes resulting from lactate accumulation [135,136]

These complexities underscore the need for tailored redox-sensitive nanocarrier design to achieve optimal therapeutic precision (140)