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3), in addition to the essentiality of glutathione that must be imported from host tissues via GshT [9], prompted us to study the putative impact of GpoA on the pneumococcal pathogenesis using an intranasal mouse model to mimic a natural pneumococcal infection [37]

B cells multiply, develop into plasma cells, and release antibodies as a result of NF- activation triggered by antigen detection by the B cell receptor (BCR) [35]