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The critical design choice was the C-terminal PGP extension: Pro-Gly-Pro provides primary resistance to proteolytic degradation, extending the compound's half-life from the minutes range of native ACTH(4-7) to approximately several hours, enabling meaningful and sustained CNS activity following administration

Batch: GF-HGHFR-B241 Assay Content: 3.64 mg Purity: 99.6 percent Identification by FTIR Spectrum: 989 Identification by Retention Time: 0.996 Molecular Ion Mass Identification: 1800 Da Bacterial Endotoxins: below 0.001 EU/mg Total Aerobic Microbial Count: 0 CFU/g Total Yeast and Mold Count: 0 CFU/g Research Applications In controlled laboratory environments, HGH Fragment 176-191 may be utilised in experimental models designed to investigate peptide signalling systems and molecular interaction pathways

Treatment of medulloblastoma cell lines with HGF induced tumor cell proliferation, anchorage-independent growth and reduced apoptosis in response to chemotherapy